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FDA Approves First CAR T-Cell Therapy for Marginal Zone Lymphoma In the US
The U.S. Food and Drug Administration has just approved a new indication for Breyanzi (Lisocabtagene maraleucel) as the first Chimeric Antigen Receptor (CAR) T-cell therapy in the U.S. for…
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4D Path Collaborates with AMD and Oracle to Scale Predictive Oncology
4D Path has created a groundbreaking platform, the patented Q-Plasia OncoReader (QPOR™), designed to directly compute cell cycle deregulation and tumor immune microenvironment dynamics to…
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Tennis Anyone? What is This Story Really About?
The story you’re about to read is about tennis. It’s also about Las Vegas. And it’s about cancer. Perhaps not in that order. Are you thoroughly dazed and confused? Keep reading. When I was 12…
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Study Reveals How Cancer Cells Become Drug Resistant
There is a quickly growing arsenal of cancer treatments available for doctors to choose from and more patients than ever before now have therapies available which provide treatment responses.…
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Even Early Cancer Detection is All About Location
A new Milken Institute report finds that access to early detection in the U.S. still depends heavily on your ZIP code, with about 9,600 early-stage breast cancer detections missed each…
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The Age of Blood Tests to Detect Cancer is Reaching Full Bloom
The latest is the first testicular cancer blood test offered in the United States An advanced test developed at UC San Diego Health can save lives and improve patient experiences by supporting…
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What NOT to Say to Someone With Cancer
No one really knows what to say when a loved one is diagnosed with cancer, and even well-meaning words can land awkwardly. What are a few things to absolutely avoid saying to your…
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Is In vivo CAR the Next Frontier of Cancer Therapy?
Imagine if cancers could be treated with an infusion of a therapy from the comfort of a doctor’s office? This infusion would not deliver chemotherapy or radiation, but rather genetic…
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Postbiotics May Be Key to Boosting Recovery After Colon Cancer Surgery
Dr. Rick Jacobson, a surgical oncologist specializing in gastrointestinal and soft tissue tumors, has a gut feeling that postbiotics can support gastrointestinal cancer patients’ recovery.…
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Grail is Looking Up
GRAIL has had a relatively short but fiery life in the hyper-competitive arena of early cancer detection. But the company has been rather quiet until recently. And for good…
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Salivary Duct Carcinoma—Treatments are Evolving, and Dentists Can Help
Salivary duct carcinoma is rarely seen by most doctors, and because of that, providing education and information about possible treatment to patients is challenging. But, Niles, Illinois-based…
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Brilliant and Kind: Alan H. Bryce Is A Rare and Wonderful Physician
When I first spoke to Alan H. Bryce, M.D., I was immediately impressed with his intellect and his compassion. He cares deeply about people, and he also happens to be a remarkable smart…
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Cancer Patients Should Always Feel Empowered to Speak Up
When I was first diagnosed with lymphoma thirty years ago, I listened to my doctors and nurses and didn’t offer much opinion. I did just about everything my doctors and nurses told…
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Bee Venom and Breast Cancer: Could Melittin Be a Breakthrough?
When most of us think of bees, we think of honey, pollination, or maybe that painful sting we try to avoid. But hidden inside that sting is a powerful molecule called melittin, the main…
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We Are All Heroes
My first real and memorable encounter with cancer, and death, happened when I was 12 years old. I had seen plenty of it on the news and in movies. But this was so close and so real. My mom…
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After the Bill: Navigating Cancer Care in a Changing Healthcare System
Part 2: Lasting Effects Red Tape and New Barriers Will Disproportionately Hurt the Sickest Beyond the funding cuts, the bill introduces a tangle of bureaucratic red tape. Medicaid recipients…
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The Leukemia and Lymphoma Society: New Name, Same Dedication
This is a monumental time for blood cancer patients. As someone who has been fighting this demon for 30 years, I want everyone to know that the Leukemia & Lymphoma Society (LLS) has always…
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Dr. Sagun Shrestha: A New Kind of Oncologist
I rarely begin a story with a statistic. But this time I’m making an exception. Why? Because I just learned that cancer rates in women in the United States under 50 are 82% higher than men the…
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Will China’s AI Breakthrough be a Game-Changer for Early Cancer Detection?
In what experts are saying is a potentially enormous development in global cancer technology, researchers in China have announced an artificial intelligence (AI) technology that can detect…
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After the Bill: Navigating Cancer Care in a Changing Healthcare System
Part 1: Initial Impact When the “One Big Beautiful Bill” was signed into law, it was sold to the public as a transformative move toward a leaner, more efficient healthcare system. The…
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A Remarkable New Cancer Treatment Is Saving Lives But Scaring Some Patients
When my cancer recurred for the fourth time earlier this year, I looked as usual for the most effective treatment. After talks with various scientists and oncologists, including my own doctor,…
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What’s New This Week
This week we bring you stories about survivors of childhood cancer, for whom researchers say genetics and treatment are key contributors to second cancer risk. We also examine a new liquid…
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For Survivors of Childhood Cancer, Genetics and Treatment are Key Contributors to Second Cancer Risk
For cancer survivors, recurrence is a real and ever-present concern. But while the threat of cancer coming back following treatment looms large for many, survivors are also at increased risk…
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Building on the Success of a New Liquid Biopsy, Researchers Develop Test to Detect Residual Cancer
Last week we brought you a story on a liquid biopsy test showing “superior sensitivity” in detecting HPV-associated head and neck cancers. Researchers at Mass Eye and Ear developed the test –…
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Is the Song Really Over?
The Who Makes Plans to End the Band’s Legendary Run and Daltrey is Knighted Last Friday national newspapers, music press, TV and radio reported that Roger Daltrey will become Sir Roger…
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New Liquid Biopsy Test Could be a Game Changer in Detecting HPV-Associated Head and Neck Cancers
Few recent developments have been as transformative to the detection of cancer as liquid biopsy. Also referred to as multi-cancer detection (MCD) or MCD assays, liquid biopsy is a test that…
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Game-Changing Medicine from Caris Life Sciences
We asked George Sledge, MD, Executive Vice President and Chief Medical Officer of Caris Life Sciences, to share the most game-changing things the company has come up with to date. For example,…
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Tumor Organoids Deliver Unprecedented Insights About Deadly Brain and Pancreatic Cancers
Cancerous tumors have complex structures that exhibit dynamic microenvironments and intricate signalling networks. Thanks to cellular mutations, accurately predicting how they react to…
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Danish Twins Study Uncovers Elevated Lymphoma Risk From Tattoo Ink
Tattooing is one of the oldest forms of body art and self-expression known to humans. Otzi the Iceman, whose 3,300-year-old body was found perfectly preserved in the Alps, had over 60 simple…
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A Combination Therapy May Help Us Treat Acute Myeloid Leukemia
When a disease has the word “acute” in the title, it usually implies a bleak prognosis. This is especially true in the case of cancers. Acute Myeloid Leukemia (AML) is a classic example. It is…
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Harvard Scientists Discover Potential Weak Link in ALK-Positive Lung Cancer Cells
Lung cancer has been strongly associated with cigarette smoking, since at least the 1960s. While smoking is still the leading cause of lung cancer cases worldwide, it is far from the only…
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Mind & Body: The Importance of Mental Health in Cancer Treatment
The Hidden Struggle: Mental Health in AYA Cancer Patients A cancer diagnosis is a life-altering moment for anyone, but for adolescents and young adults (AYAs), it can be particularly…
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Planning for the Uncertain: The Long-Term Goals of Children with Liver Cancer
How many of your childhood dreams have come true? Youth is a time for making plans and envisioning the future. As you grow up, priorities evolve and plans change, but the journey to where you…
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Brushing Off Cancer: How Oral Health Protects More Than Your Teeth
Did you know that keeping your mouth clean is about more than fresh breath or avoiding cavities? What if it was about something much bigger, like cancer? Science is beginning to shout what…
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ELAHERE Phase 3 Trial Results Are a Game-Changer for Ovarian Cancer Treatments
Ovarian cancer is the deadliest form of gynecological cancer that kills an estimated 12,700 women each year in the United States. Since 70% of all new cases are diagnosed at advanced stages,…
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Historic Day for Cancer Patients That Will Undoubtedly Save Lives
This week marks a historic moment for the cancer industry and a potentially huge gift for patients. Just days ago, Stand Up To Cancer, the non-profit cancer…
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The Heroes of Cancer
Cancer is a monster. A killing machine. I’m sure that nearly everyone reading this story knows someone who has had cancer. Sadly, such has been the case seemingly forever. The good news? After…
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Real-Time 3D Telemedicine Enhances Surgical Consultations in Ghana: A Groundbreaking Study
Addressing Healthcare Disparities with Technology In Ghana, a nation of over 34 million people, the scarcity of specialized surgeons poses significant challenges to patient care, particularly…
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Cancer-Causing Cells Participate in Cooperative Scavenging
We still don’t know everything about cancer, but a new NYU study discovered just one more piece of the puzzle on our way to understanding tumor formation. Cancer experts have established how…
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Red vs. White: Study Settles the Debate Around the Health Benefits of Wine
The idea that regular, moderate wine consumption carries health benefits and can result in greater longevity is arguably as old as the libation itself. Ancient civilizations like…
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We Are All Heroes
My first real encounter with cancer was when I was 8 years old. My mom and dad had brought me, my older sister and older brother to visit my Grampa, who was always simply the best! We…
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Seeing the Light
OK. Here we go. Decision made. It’s time to do the Bispecific Antibody treatment, to fight my aggressive lymphoma. The first day of my infusion was a smooth ride. By the end of the…
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A New Study Indicates that Frequent Blood Donations May Help Lower the Risk of Leukemia
Donating your blood is a humanitarian activity that can save lives. According to the American Red Cross, a unit of blood is required once every two seconds to save the lives of trauma victims,…
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Difficult Conversations: Helping Families Navigate Pediatric Nasopharyngeal Carcinoma Treatment Side Effects
How would you tell a parent of a child impacted by cancer that the medicine you will use to combat it could also harm them? That’s a challenge oncologists helping children beat…
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Dr. ChatGPT is Not Ready for Primetime (Yet) in Pediatric Non-small Cell Lung Cancer Care
Would you trust a life-altering medical treatment formulated by ChatGPT? Large Language Models (LLM) are part of everyday life for students and professionals as tools that help them accomplish…
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Particle Accelerators & Flash Therapy: The Future of Radiotherapy for Cancer Patients
Cancer treatment has evolved significantly over the past few decades, with advancements in radiation therapy playing a critical role in improving patient outcomes given over half of all…
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Male Breast Cancer — Awareness Can Save Lives
When Cailynn Madigan was scared of thunderstorms as a child, her grandfather, who was a stormchaser, would ease her fears by talking to her about the science of weather. He explained many…
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Genetically Modified Herpes Virus May Help Skin Cancer Patients Avoid Complicated Reconstruction Surgeries
The sudden appearance of a mole on your skin is a genuine cause for concern. It could be a sign of melanoma, a highly aggressive form of skin cancer. Thankfully, melanomas account for just 1%…
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PAC-MANN: A Game-Changer in Pancreatic Cancer Detection and Treatment
Pancreatic cancer is one of the deadliest forms of cancer, often diagnosed at an advanced stage when treatment options are limited. With a five-year survival rate right around 10%, this…
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Massive Machine Learning Enabled Data Analysis Offers Key Insights into Efficacy of Immunotherapy
The convergence of cancer treatment and artificial intelligence (AI) is one of the most impactful developments in modern healthcare, and as a result, a topic we have covered extensively at…
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How Everyday Trauma Affects Oncologists Helping Children Beat Nerve Tumors
What if caring too much about your patients could harm you? Helping children beat nerve tumors is not easy. Beyond the complexities of managing symptoms and controlling progression, continuous…
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Minoxidil Can Help Breast Cancer Patients Combat Chemotherapy Induced Hair Loss
Breast cancer is the most common type of cancer among women, accounting for around 30% of all cancers. A breast cancer diagnosis is a life-altering event that can have a massive impact on the…
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How Home Inspections for Radon Can Help Mitigate Cancer Risk
Radon is odorless and present in many homes. It’s the leading cause of lung cancer in nonsmokers, but there are ways to decrease your risk with a few precautions. Most people are aware that…
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New Research Indicates that Lifetime Risk for Cancer May Begin Even Before Birth
The role played by genetics in increasing cancer risk is quite well known. If there is a family history of cancer in more than one close relative, your risk of contracting the disease in your…
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Working with Your Dentist During Cancer Treatment
Cancer treatments have side effects that show up on the mouth and teeth – but dentists are equipped to mitigate them. Every day we have more information about the many ways dental health can…
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Using DNA-Tagged Gold Nanoparticles for Highly Accurate Targeted Attacks on Cancer Cells
When we think about gold, the first thing that usually comes to mind is jewelry, possibly followed by coins and ingots. Aside from its economic and ornamental value, the precious metal also…
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Biodexa Receives US FDA Fast Track Designation for eRapa in Familial Adenomatous Polyposis
Familial Adenomatous Polyposis (FAP) is characterized as a proliferation of polyps in the colon and/or rectum, usually occurring in the mid-teens. If left untreated, it universally leads to…
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The Global Effort to Address Pediatric Cancer Medication Shortages in Low-Income Countries
Do babies born in certain places have a higher risk of dying of cancer? The CEO and president of St. Jude Children’s Research Hospital James R. Downing believes they do: “Location is the…
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PAC-MANN Test Identifies Early Stage Pancreatic Cancer
A new test called PAC-MANN, being researched at Oregon Health & Science University (OHSU), is hoping to take a bite out of the time and costs of detecting pancreatic cancer. The study…
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Flower-Shaped Nanoparticles May Help Us Target Tumors with Greater Precision (And Fewer Side Effects)
Avoiding collateral damage is one of the main concerns scientists have regarding developing more effective cancer medication. Many of the popular chemotherapy drugs tend to be cytotoxic agents…
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Float Like a Butterfly, Better Analyze Biopsies
The saying goes something like that, right? According to researchers at the University of California San Diego (UCSD), the perfect one-two punch in cancer detection may be found in a biopsy…
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How Vorasidenib Is Changing The Lives of Young Adults Suffering From Incurable Low-Grade Gliomas
Low-grade gliomas (LGG) are incurable, slow-growing malignant brain tumors commonly found in young adults between the ages of 20-40. Patients diagnosed with this type of cancer can expect to…
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Navigating Uncharted Territory: CAR-T for Ovarian Cancer
When Marisol Gallagher got frustrated with taking antibiotics for her diverticulitis, just after her 50th birthday in the summer of 2013, she decided to undergo a colon resection surgery. When…
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Parental Smoking Multiplies the Risk of Retinoblastoma in Children. Why is Tobacco Still Appealing?
What damaging habit in your life would you like to change? We all do things we know are bad for our health, but we still do them. Whether indulging in too much cake or exercising less than…
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Lung Cancer Cells’ Ability to Go “Off-Grid” May Offer Clues into Both the Disease’s Aggressiveness and Vulnerability
In our increasingly connected and hectic world, the term “off-grid” has come to represent not only a self-sufficient lifestyle, but also a rejection of the status quo and many of the creature…
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The Human Touch: Moffitt Study Shows AI Boosts Efficacy, But Doctors Remain A Big Part of the Equation
Regular readers of our magazine certainly don’t need me to tell you how exciting AI (artificial intelligence) is as a new and versatile tool for oncologists. AI is already helping save…
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From Pixels to Precision: “Radiomics” Transforms Cancer Care
The term “omics” refers to a broad field of biological science dedicated to understanding and cataloging the full range of information within cells, tissues, or entire organisms. Each omics…
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Researchers Have Developed A Light Activated System to Kill Aggressive Cancer Cells Inside the Body
Using light energy as a weapon is a popular trope in science fiction. The planet-killing Death Star from the Star Wars movies is probably the biggest example. In real life, the US military is…
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Of Dogs and Diagnostics: Calviri is Focused on Early Detection and Vaccines for Both Canines and Their Human Companions
In today’s fight against cancer, there are few developments as transformative as liquid biopsies and vaccines. For Phoenix-based biotech company, Calviri, its goal to end cancer worldwide has…
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A Rough Week for RFK Jr.
It’s been a long journey for cancer vaccine scientists. But they are finally on the brink of something truly remarkable. However, this week, Robert F. Kennedy Jr. challenged that world…
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Cancer Vaccines Continue to Save Lives Despite New Hurdles to Overcome
What are Cancer Vaccines Cancer remains one of the most formidable challenges in modern medicine, claiming millions of lives each year. However, the landscape of cancer treatment is evolving,…
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Alpha DaRT: A Promising New Pancreatic Cancer Treatment for Patients with Limited Options
The prognosis that accompanies a pancreatic cancer diagnosis is typically grim, largely because the disease often shows few or no symptoms until it has reached an advanced stage and…
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Tumor Boards for Pediatric Central Nervous System Cancer: Why Clinical Minds Working Together Matters
Are you afraid Artificial Intelligence (AI) will replace your job? It’s too soon to evaluate AI’s impact on the workforce. Nevertheless, the idea that machines will make some human endeavors…
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How Treating Golgi Bodies With Hydrogen Sulfide Can Help Us Re-energize Tumor Killing T-Cells
The human immune system has an arsenal of different tools to kill cancer cells, including T cells, neutrophils, and macrophages. Out of the trio, T cells are the most effective killing…
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We Now Know Why 50% of Breast Cancer Patients Don’t Respond Well to Tamoxifen
Tamoxifen is a critical drug in the fight against breast cancer. As an estrogen-blocker, it has a dual role as a treatment drug and as a prophylactic (preventive medicine) for estrogen…
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New Research Findings Could Reshape Glioblastoma Treatment and Disease Monitoring
Glioblastoma is a fast-growing and aggressive brain tumor, often considered one of the toughest types of cancer to fight. According to the American Association of Neurological Surgeons, nearly…
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Understanding Increased Cancer Diagnoses in Gen X and Millennial Cohorts
A 2024 study from The Lancet raised concerns about increased cancer rates in patients aged 50 and under. Experts point to signs of hope behind these results. In August of last year academic…
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EXCLUSIVE: Paige Breaks New Ground in Cancer Digital Pathology Industry
Today, Paige, a leading AI (artificial intelligence) company that is focused on cancer, announced its third FDA recognition—this time its FullFocus™ digital pathology image viewer…
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Information is Not Enough: Young Bone and SofT Tissue Cancer Survivors Want to Learn in Their Own Terms
How many people understand the unique difficulties you’ve overcome to be the person you are today? Not too many. For young survivors of orthopedic cancer, intimate knowledge of what it means…
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Amid Growing Concerns Around the Link Between Alcohol and Cancer, Surgeon General Sounds the Alarm
In recent years, the link between alcohol consumption and cancer has become increasingly clear. Various studies have established a strong correlation between the two, largely attributed to…
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Jimmy Carter: An American Icon and Cancer Warrior Takes His Final Bow
I had a memorable conversation with former President Jimmy Carter back in the 1980’s that I’ll never forget. The interview was set up to help publicize the former president’s…
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Watching Tumor Cells Compete With Each Other Can Help Us Combat Drug Resistance In Multiple Myeloma And Other Cancers
The COVID-19 pandemic taught us about the dangers of viral mutations. According to the WHO, by 2023, at least nine prominent variants of the Coronavirus were in circulation around the…
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FDA Approves the First and Only Therapy for Patients with NRG1+ Pancreatic Adenocarcinoma and Non–Small Cell Lung Cancer (NSCLC)
On December 4, 2024, the U.S. Food and Drug Administration (FDA) granted accelerated approval for Merus N.V.’s BIZENGRI® (zenocutuzumab-zbco), a breakthrough therapy for patients with advanced…
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EXCLUSIVE: Turning the Paige – Our Favorite Scientists
If you’ve read our magazine these last two years, you’ve witnessed the flurry of new and potentially lifechanging cancer technologies that are beginning to be available to oncologists,…
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Accelerated Life: Making Hodgkin and non-Hodgkin Lymphomas Young Survivors’ Years Count
Is the passage of time the same for everyone? According to research, it is not for childhood cancer survivors. Children who survive Hodgkin and non-Hodgkin lymphomas may biologically age…
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GAME CHANGER: Generation X and Millennials Have Higher Risk of Developing Cancers
As 2024 comes to an end, it has been a year of remarkable discoveries alongside growing challenges in cancer research. A major study in The Lancet revealed a concerning trend: cancer rates are…
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GAME CHANGER: Guardant Shield Test Summer Announcement Bears Continued Celebration as the Year Closes
Colorectal cancers continue to rise across multiple demographics, but many public and private entities are looking for easier ways to help patients get simpler screening. Earlier this year we…
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GAME CHANGER: Zanubrutinib – A Safer BTK-Inhibitor That Reduces Death/Progression Risk in CLL and SLL By 71%
Chronic Lymphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL) are two closely related types of white blood cell cancers that are typically diagnosed in older adults. As of 2024, at…
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The GAME CHANGERS
In the cancer space, more innovations than ever before are showing the potential to forever alter the course of cancer detection, prevention, and treatment. Perhaps the most impressive game…
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GAME CHANGER: FDA Fast-Track Designation to OBX-115
People with advanced or metastatic melanoma and other solid tumors may soon have more options for treatment. In July 2024, Obsidian Therapeutics, Inc. earned FDA Fast Track Designation…
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GAME CHANGER: Vorasidenib for Brain Cancer Treatment
The recent approval of Vorasidenib by the FDA represents a significant breakthrough in the treatment of brain cancer by being the first systemic therapy specifically targeting IDH-mutant…
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GAME CHANGER: FDA Approves BIZENGRI® – The First and Only Therapy for NRG1+ Pancreatic Adenocarcinoma and Non–Small Cell Lung Cancer (NSCLC)
As 2024 draws to a close, the FDA announces a new game-changing approval for rare, difficult-to-treat cancers. On December 4, accelerated approval was granted to BIZENGRI®…
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BREAKING: City of Hope Scientists Uncover Protein That Helps Cancer Cells Dodge CAR T Cell Therapy
Discovery could lead to new treatments for blood cancer patients currently facing limited options Big news is breaking today in the cancer universe that could save many lives and give patients…
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Taylor Swift Can Cure Cancer
I just watched an inspirational news piece about Rocky Hill, a young man fighting persistent brain cancer, who finds strength and solace through Taylor Swift’s music. This brave 20 year old…
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The New Miracle Worker
There are cancer warriors, and then there is Dick Vitale, the longtime basketball analyst and former coach who announced this week that he is cancer-free after his fourth fight with the…
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Understanding the Links Between Alcohol and Cancer
Cancer rates are increasing in people ages 50 and under, and de-stigmatizing alcohol can decrease risk factors. There’s more public knowledge than ever about the risks of alcohol consumption.…
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Adjusting Omega Fats + Fish Oil Prove a Powerful Dietary Combo in Slowing Prostate Cancer Growth
A person’s diet can impact cancer in a variety of ways. Studies have identified dietary habits as a key factor in decreasing cancer risk, as well as slowing the progression of the disease. The…
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Charting A New Course
It’s been another year of high achievement for the American Society of Hematology (ASH), whose 66th ASH Annual Meeting and Exposition this week in San Diego showed us all that this is one…
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Detecting Oral Cancer Early With Biomarkers
Most dentists screen for oral cancer during routine checkups. They typically do a visual examination for white patches, sores, or lumps on the cheek lining, floor and roof of the mouth, gums,…
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The FOXA1 Protein Is No Longer “Undruggable” – Here is Why It Matters for Breast Cancer Research
Around 80% of all breast cancers fall into the category of hormone-receptor-positive (HR+) cancers. Tumor growth in these cancers is fueled by the presence of naturally occurring human sex…
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